File forf= new File(rnad+"/strand_rna_884-rrp6d_sd_20121119_sacCer1_for.wig");
File revf= new File(rnad+"/strand_rna_884-rrp6d_sd_20121119_sacCer1_rev.wig");
File rd= new File(dir+"/data/chip-seq/norm/peak_new/rand/three");
GenomicRegionsBuilder gb= new GenomicRegionsModifier(new BedReader(anno).getGenomicRegionsBuilder()).getThreePrimeEnds(150, 0);
LandscapeBuilder lbf= new BedGraphReader(forf).getLandscapeBuilder();
LandscapeBuilder lbr= new BedGraphReader(revf).getLandscapeBuilder();
new RandomNew(927, rd, lbf, lbr, gb);