private CompareToReference2 c2r;
private Map<Integer, Long> qualityCounts;
private Map<Integer, Long> qualityMismatches;
public void run(String input, String ref) throws IOException {
c2r = new CompareToReference2();
c2r.init(ref);
qualityMismatches = new HashMap<Integer, Long>();
qualityCounts = new HashMap<Integer, Long>();